Cambridge Healthtech Institute’s 3rd Annual
Induced Proximity-Based Drug Discovery
Modulating Binding, Localization and Cellular Interactions for Desirable Therapeutic Outcomes
September 28, 2026
A new generation of drug modalities is being developed to leverage existing cellular machinery to disrupt protein-protein interactions (PPI), to induce proximity between key effector targets, and to seek out previously “undruggable” targets for therapeutic intervention. Cambridge Healthtech Institute’s symposium focused on Induced Proximity-Based Drug Discovery brings together experts to discuss the use of innovative chemistries and novel techniques to unravel complex cell biology and induce interactions that can trigger degradation, stabilization, transcription and more to bring about the desired physiological response.
Coverage will include, but is not limited to:
- Design and optimization of novel chemistries and modalities for inducing proximity
- Use of PROTACs, molecular glues, bifunctional peptides, antibody conjugates, T-cell engagers
- Exploring covalency, conjugation and other strategies for inducing proximity
- Emerging modalities for inducing stabilization, phosphorylation, degradation and more
- Targeting new ligases and enzymes for disrupting protein-protein interactions
- Emerging assays, probes and linker technologies to screen for proximity
- Pursuing induced proximity approaches for drugging challenging targets
Who should attend:
- Biologists tackling difficult-to-drug targets in search of new cellular mechanisms to induce proximity
- Chemists and biologists exploring tools and strategies for evaluating novel drug modalities
- Medicinal chemists driving the design and synthesis of next-generation drug-like molecules
- Target discovery scientists working on target engagement, mechanism-of-action, and deconvolution studies
- Assay developers and screening specialists seeking next-generation methodologies
- Computational scientists applying AI-driven drug design, screening, and optimization
- Scientists focused on lead optimization, including prediction of drug-like properties
The deadline for priority consideration is March 13, 2026.
All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.
Opportunities for Participation: